Katharine Irvine

Biography

Dr Katharine Irvine co-leads the Macrophage Biology lab at Mater Research-UQ. She completed her PhD in 2004 at the UQ IMB, followed by postdoctoral positions at IMB, UQ Diamantina Institute and UQ School of Medicine before joining Mater Research in 2017. She has worked on diverse aspects of fundamental macrophage biology and their pathophysiological roles in homeostasis, inflammation and infections throughout her career. She has a particular interest in macrophage contributions to the progression and complications of chronic liver disease, and in translational research focused on macrophages in metabolic diseases more generally. She was awarded the inaugural Australian Liver Foundation Pauline Hall Fellowship in 2012, and since then has enjoyed extensive clinical collaborations and has led and contributed to projects spanning the spectrum of preclinical-clinical research in liver disease. She is an elected member of the Gastroenterological Society of Australia Liver Faculty (2021-2023). Dr Irvine has diverse technical expertise spanning genomics and bioinformatics, molecular and cellular biology, in vivo investigations in mice and rats, as well as clinical research design and analysis. She has received over $3 million in competitive funding throughout her career, and has over 90 publications that have been cited more than 3000 times (h-index 29).  



Publications

2022

Stables, Jennifer; Green, Emma K; Sehgal, Anuj; Patkar, Omkar L; Keshvari, Sahar; Taylor, Isis; Ashcroft, Maisie E; Grabert, Kathleen; Wollscheid-Lengeling, Evi; Szymkowiak, Stefan; McColl, Barry W; Adamson, Antony; Humphreys, Neil E; Mueller, Werner; Starobova, Hana; Vetter, Irina; Shabestari, Sepideh Kiani; Blurton-Jones, Matthew M; Summers, Kim M; Irvine, Katharine M; Pridans, Clare; Hume, David A

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling (Journal Article)

In: Development, vol. 149, no. 8, 2022, ISSN: 1477-9129.

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Keshvari, Sahar; Genz, Berit; Teakle, Ngari; Caruso, Melanie; Cestari, Michelle F; Patkar, Omkar L; Tse, Brian W C; Sokolowski, Kamil A; Ebersbach, Hilmar; Jascur, Julia; MacDonald, Kelli P A; Miller, Gregory; Ramm, Grant A; Pettit, Allison R; Clouston, Andrew D; Powell, Elizabeth E; Hume, David A; Irvine, Katharine M

Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease (Journal Article)

In: Dis Model Mech, 2022, ISSN: 1754-8411.

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2021

Batoon, Lena; Millard, Susan M.; Raggatt, Liza J.; Sandrock, Cheyenne; Pickering, Edmund; Williams, Kyle; Sun, Lucas W. H.; Wu, Andy C.; Irvine, Katharine M.; Pivonka, Peter; Glatt, Vaida; Wullschleger, Martin E.; Hume, David A.; Pettit, Allison R.

Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones (Journal Article)

In: Biomaterials, vol. 275, pp. 120936, 2021, ISSN: 0142-9612.

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Keshvari, Sahar; Caruso, Melanie; Teakle, Ngari; Batoon, Lena; Sehgal, Anuj; Patkar, Omkar L.; Ferrari-Cestari, Michelle; Snell, Cameron E.; Chen, Chen; Stevenson, Alex; Davis, Felicity M.; Bush, Stephen J.; Pridans, Clare; Summers, Kim M.; Pettit, Allison R.; Irvine, Katharine M.; Hume, David A.

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation (Journal Article)

In: PLOS Genetics, vol. 17, no. 6, pp. e1009605, 2021, ISSN: 1553-7404.

(Abstract | Links | BibTeX | Altmetric)

Hume, David A.; Caruso, Melanie; Keshvari, Sahar; Patkar, Omkar L.; Sehgal, Anuj; Bush, Stephen J.; Summers, Kim M.; Pridans, Clare; Irvine, Katharine M.

The Mononuclear Phagocyte System of the Rat (Journal Article)

In: The Journal of Immunology, vol. 206, no. 10, pp. 2251–2263, 2021, ISSN: 0022-1767, 1550-6606.

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Sehgal, Anuj; Irvine, Katharine M; Hume, David A

Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair (Journal Article)

In: Semin Immunol, vol. 54, pp. 101509, 2021, ISSN: 1096-3618.

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Keshvari, Sahar; Caruso, Melanie; Teakle, Ngari; Batoon, Lena; Sehgal, Anuj; Patkar, Omkar L; Ferrari-Cestari, Michelle; Snell, Cameron E; Chen, Chen; Stevenson, Alex; Davis, Felicity M; Bush, Stephen J; Pridans, Clare; Summers, Kim M; Pettit, Allison R; Irvine, Katharine M; Hume, David A

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation (Journal Article)

In: PLOS Genetics, vol. 17, no. 6, pp. e1009605, 2021, ISSN: 1553-7404, (Publisher: Public Library of Science).

(Abstract | Links | BibTeX | Altmetric)

Batoon, Lena; Millard, Susan M; Raggatt, Liza J; Sandrock, Cheyenne; Pickering, Edmund; Williams, Kyle; Sun, Lucas W H; Wu, Andy C; Irvine, Katharine M; Pivonka, Peter; Glatt, Vaida; Wullschleger, Martin E; Hume, David A; Pettit, Allison R

Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones (Journal Article)

In: Biomaterials, vol. 275, pp. 120936, 2021, ISSN: 0142-9612.

(Abstract | Links | BibTeX | Altmetric)

Millard, Susan M; Heng, Ostyn; Opperman, Khatora S; Sehgal, Anuj; Irvine, Katharine M; Kaur, Simranpreet; Sandrock, Cheyenne J; Wu, Andy C; Magor, Graham W; Batoon, Lena; Perkins, Andrew C; Noll, Jacqueline E; Zannettino, Andrew C W; Sester, David P; Levesque, Jean-Pierre; Hume, David A; Raggatt, Liza J; Summers, Kim M; Pettit, Allison R

Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues (Journal Article)

In: Cell Rep, vol. 37, no. 8, pp. 110058, 2021, ISSN: 2211-1247.

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Patkar, O. L.; Caruso, M.; Teakle, N.; Keshvari, S.; Bush, S. J.; Pridans, C.; Belmer, A.; Summers, K. M.; Irvine, K. M.; Hume, D. A.

Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations (Journal Article)

In: Neurobiology of Disease, vol. 151, 2021, ISSN: 09699961, (Publisher: Academic Press Inc.).

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Pridans, C.; Irvine, K. M.; Davis, G. M.; Lefevre, L.; Bush, S. J.; Hume, D. A.

Transcriptomic Analysis of Rat Macrophages (Journal Article)

In: Frontiers in Immunology, vol. 11, 2021, ISSN: 16643224, (Publisher: Frontiers Media S.A.).

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2020

Grabert, Kathleen; Sehgal, Anuj; Irvine, Katharine M.; Wollscheid-Lengeling, Evi; Ozdemir, Derya D.; Stables, Jennifer; Luke, Garry A.; Ryan, Martin D.; Adamson, Antony; Humphreys, Neil E.; Sandrock, Cheyenne J.; Rojo, Rocio; Verkasalo, Veera A.; Mueller, Werner; Hohenstein, Peter; Pettit, Allison R.; Pridans, Clare; Hume, David A.

A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System (Journal Article)

In: The Journal of Immunology, vol. 205, no. 11, pp. 3154–3166, 2020, ISSN: 0022-1767, 1550-6606.

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Irvine, Katharine M.; Caruso, Melanie; Cestari, Michelle Ferrari; Davis, Gemma M.; Keshvari, Sahar; Sehgal, Anuj; Pridans, Clare; Hume, David A.

Analysis of the impact of CSF‐1 administration in adult rats using a novel textitCsf1r ‐mApple reporter gene (Journal Article)

In: Journal of Leukocyte Biology, vol. 107, no. 2, pp. 221–235, 2020, ISSN: 0741-5400, 1938-3673.

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Hume, D. A.; Caruso, M.; Ferrari-Cestari, M.; Summers, K. M.; Pridans, C.; Irvine, K. M.

Phenotypic impacts of CSF1R deficiencies in humans and model organisms (Journal Article)

In: Journal of Leukocyte Biology, vol. 107, no. 2, pp. 205–219, 2020, ISSN: 07415400, (Publisher: John Wiley and Sons Inc.).

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2019

Hume, D. A.; Irvine, K. M.; Pridans, C.

The Mononuclear Phagocyte System: The Relationship between Monocytes and Macrophages (Journal Article)

In: Trends in Immunology, vol. 40, no. 2, pp. 98–112, 2019, ISSN: 14714906, (Publisher: Elsevier Ltd).

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Irvine, K. M.; Ratnasekera, I.; Powell, E. E.; Hume, D. A.

Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293) (Journal Article)

In: Frontiers in Immunology, vol. 10, no. APR, 2019, ISSN: 16643224, (Publisher: Frontiers Media S.A.).

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Irvine, K. M.; Ratnasekera, I.; Powell, E. E.; Hume, D. A.

Casuses and consequences of innate immune dysfucntion in cirrhosis (Journal Article)

In: Frontiers in Immunology, vol. 10, no. FEB, 2019, ISSN: 16643224, (Publisher: Frontiers Media S.A.).

(Abstract | Links | BibTeX | Altmetric)

2018

Waddell, L. A.; Lefevre, L.; Bush, S. J.; Raper, A.; Young, R.; Lisowski, Z. M.; McCulloch, M. E. B.; Muriuki, C.; Sauter, K. A.; Clark, E. L.; Irvine, K. M.; Pridans, C.; Hope, J. C.; Hume, D. A.

ADGRE1 (EMR1, F4/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages (Journal Article)

In: Frontiers in Immunology, vol. 9, no. OCT, 2018, ISSN: 16643224, (Publisher: Frontiers Media S.A.).

(Abstract | Links | BibTeX | Altmetric)

Pridans, C.; Sauter, K. A.; Irvine, K. M.; Davis, G. M.; Lefevre, L.; Raper, A.; Rojo, R.; Nirmal, A. J.; Beard, P.; Cheeseman, M.; Hume, D. A.

Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats (Journal Article)

In: American Journal of Physiology - Gastrointestinal and Liver Physiology, vol. 314, no. 3, pp. G388–G398, 2018, ISSN: 01931857, (Publisher: American Physiological Society).

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2013

Shakespear, M. R.; Hohenhaus, D. M.; Kelly, G. M.; Kamal, N. A.; Gupta, P.; Labzin, L. I.; Schroder, K.; Garceau, V.; Barbero, S.; Iyer, A.; Hume, D. A.; Reid, R. C.; Irvine, K. M.; Fairlie, D. P.; Sweet, M. J.

Histone deacetylase 7 promotes toll-like receptor 4-dependent proinflammatory gene expression in macrophages (Journal Article)

In: Journal of Biological Chemistry, vol. 288, no. 35, pp. 25362–25374, 2013, ISSN: 00219258.

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2012

Schroder, K.; Irvine, K. M.; Taylor, M. S.; Bokil, N. J.; Cao, K. -A. Le; Masterman, K. -A.; Labzin, L. I.; Semple, C. A.; Kapetanovic, R.; Fairbairn, L.; Akalin, A.; Faulkner, G. J.; Baillie, J. K.; Gongora, M.; Daub, C. O.; Kawaji, H.; McLachlan, G. J.; Goldman, N.; Grimmond, S. M.; Carninci, P.; Suzuki, H.; Hayashizaki, Y.; Lenhard, B.; Hume, D. A.; Sweet, M. J.

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages (Journal Article)

In: Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 16, pp. E944–E953, 2012, ISSN: 00278424.

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2011

Zuylen, W. J.; Garceau, V.; Idris, A.; Schroder, K.; Irvine, K. M.; Lattin, J. E.; Ovchinnikov, D. A.; Perkins, A. C.; Cook, A. D.; Hamilton, J. A.; Hertzog, P. J.; Stacey, K. J.; Kellie, S.; Hume, D. A.; Sweet, M. J.

Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis (Journal Article)

In: PLoS ONE, vol. 6, no. 1, 2011, ISSN: 19326203.

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2010

Kubosaki, A.; Lindgren, G.; Tagami, M.; Simon, C.; Tomaru, Y.; Miura, H.; Suzuki, T.; Arner, E.; Forrest, A. R. R.; Irvine, K. M.; Schroder, K.; Hasegawa, Y.; Kanamori-Katayama, M.; Rehli, M.; Hume, D. A.; Kawai, J.; Suzuki, M.; Suzuki, H.; Hayashizaki, Y.

The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells (Journal Article)

In: Molecular Immunology, vol. 47, no. 14, pp. 2295–2302, 2010, ISSN: 01615890.

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Halili, M. A.; Andrews, M. R.; Labzin, L. I.; Schroder, K.; Matthias, G.; Cao, C.; Lovelace, E.; Reid, R. C.; Le, G. T.; Hume, D. A.; Irvine, K. M.; Matthias, P.; Fairlie, D. P.; Sweet, M. J.

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS (Journal Article)

In: Journal of Leukocyte Biology, vol. 87, no. 6, pp. 1103–1114, 2010, ISSN: 07415400.

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2009

Hume, D. A.; Schroder, K.; Irvine, K. M.

The impact of CAGE data on understanding macrophage transcriptional biology (Book)

Pan Stanford Publishing Pte. Ltd., 2009, ISBN: 978-981-4241-34-2, (Publication Title: Cap-Analysis Gene Expression (CAGE): The Science of Decoding Genes Transcription).

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Goh, F.; Irvine, K. M.; Lovelace, E.; Donnelly, S.; Jones, M. K.; Brion, K.; Hume, D. A.; Kotze, A. C.; Dalton, J. P.; Ingham, A.; Sweet, M. J.

Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling (Journal Article)

In: Immunology, vol. 127, no. 3, pp. 326–337, 2009, ISSN: 00192805.

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Faulkner, G. J.; Kimura, Y.; Daub, C. O.; Wani, S.; Plessy, C.; Irvine, K. M.; Schroder, K.; Cloonan, N.; Steptoe, A. L.; Lassmann, T.; Waki, K.; Hornig, N.; Arakawa, T.; Takahashi, H.; Kawai, J.; Forrest, A. R. R.; Suzuki, H.; Hayashizaki, Y.; Hume, D. A.; Orlando, V.; Grimmond, S. M.; Carninci, P.

The regulated retrotransposon transcriptome of mammalian cells (Journal Article)

In: Nature Genetics, vol. 41, no. 5, pp. 563–571, 2009, ISSN: 10614036.

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Suzuki, H.; Forrest, A. R. R.; Nimwegen, E. Van; Daub, C. O.; Balwierz, P. J.; Irvine, K. M.; Lassmann, T.; Ravasi, T.; Hasegawa, Y.; Hoon, M. J. L. De; Katayama, S.; Schroder, K.; Carninci, P.; Tomaru, Y.; Kanamori-Katayama, M.; Kubosaki, A.; Akalin, A.; Ando, Y.; Arner, E.; Asada, M.; Asahara, H.; Bailey, T.; Bajic, V. B.; Bauer, D.; Beckhouse, A. G.; Bertin, N.; Björkegren, J.; Brombacher, F.; Bulger, E.; Chalk, A. M.; Chiba, J.; Cloonan, N.; Dawe, A.; Dostie, J.; Engström, P. G.; Essack, M.; Faulkner, G. J.; Fink, J. L.; Fredman, D.; Fujimori, K.; Furuno, M.; Gojobori, T.; Gough, J.; Grimmond, S. M.; Gustafsson, M.; Hashimoto, M.; Hashimoto, T.; Hatakeyama, M.; Heinzel, S.; Hide, W.; Hofmann, O.; Hörnquist, M.; Huminiecki, L.; Ikeo, K.; Imamoto, N.; Inoue, S.; Inoue, Y.; Ishihara, R.; Iwayanagi, T.; Jacobsen, A.; Kaur, M.; Kawaji, H.; Kerr, M. C.; Kimura, R.; Kimura, S.; Kimura, Y.; Kitano, H.; Koga, H.; Kojima, T.; Kondo, S.; Konno, T.; Krogh, A.; Kruger, A.; Kumar, A.; Lenhard, B.; Lennartsson, A.; Lindow, M.; Lizio, M.; MacPherson, C.; Maeda, N.; Maher, C. A.; Maqungo, M.; Mar, J.; Matigian, N. A.; Matsuda, H.; Mattick, J. S.; Meier, S.; Miyamoto, S.; Miyamoto-Sato, E.; Nakabayashi, K.; Nakachi, Y.; Nakano, M.; Nygaard, S.; Okayama, T.; Okazaki, Y.; Okuda-Yabukami, H.; Orlando, V.; Otomo, J.; Pachkov, M.; Petrovsky, N.; Plessy, C.; Quackenbush, J.; Radovanovic, A.; Rehli, M.; Saito, R.; Sandelin, A.; Schmeier, S.; Schönbach, C.; Schwartz, A. S.; Semple, C. A.; Sera, M.; Severin, J.; Shirahige, K.; Simons, C.; Laurent, G. St.; Suzuki, M.; Suzuki, T.; Sweet, M. J.; Taft, R. J.; Takeda, S.; Takenaka, Y.; Tan, K.; Taylor, M. S.; Teasdale, R. D.; Tegnér, J.; Teichmann, S.; Valen, E.; Wahlestedt, C.; Waki, K.; Waterhouse, A.; Wells, C. A.; Winther, O.; Wu, L.; Yamaguchi, K.; Yanagawa, H.; Yasuda, J.; Zavolan, M.; Hume, D. A.; Arakawa, T.; Fukuda, S.; Imamura, K.; Kai, C.; Kaiho, A.; Kawashima, T.; Kawazu, C.; Kitazume, Y.; Kojima, M.; Miura, H.; Murakami, K.; Murata, M.; Ninomiya, N.; Nishiyori, H.; Noma, S.; Ogawa, C.; Sano, T.; Simon, C.; Tagami, M.; Takahashi, Y.; Kawai, J.; Hayashizaki, Y.

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line (Journal Article)

In: Nature Genetics, vol. 41, no. 5, pp. 553–562, 2009, ISSN: 10614036.

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Mar, J. C.; Kimura, Y.; Schroder, K.; Irvine, K. M.; Hayashizaki, Y.; Suzuki, H.; Hume, D.; Quackenbush, J.

Data-driven normalization strategies for high-throughput quantitative RT-PCR (Journal Article)

In: BMC Bioinformatics, vol. 10, 2009, ISSN: 14712105.

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Kawaji, H.; Severin, J.; Lizio, M.; Waterhouse, A.; Katayama, S.; Irvine, K. M.; Hume, D. A.; Forrest, A. R. R.; Suzuki, H.; Carninci, P.; Hayashizaki, Y.; Daub, C. O.

The FANTOM web resource: From mammalian transcriptional landscape to its dynamic regulation (Journal Article)

In: Genome Biology, vol. 10, no. 4, 2009, ISSN: 14747596.

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Irvine, K. M.; Andrews, M. R.; Fernandez-Rojo, M. A.; Schroder, K.; Burns, C. J.; Su, S.; Wilks, A. F.; Parton, R. G.; Hume, D. A.; Sweet, M. J.

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages (Journal Article)

In: Journal of Leukocyte Biology, vol. 85, no. 2, pp. 278–288, 2009, ISSN: 07415400.

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Taft, R. J.; Glazov, E. A.; Cloonan, N.; Simons, C.; Stephen, S.; Faulkner, G. J.; Lassmann, T.; Forrest, A. R. R.; Grimmond, S. M.; Schroder, K.; Irvine, K.; Arakawa, T.; Nakamura, M.; Kubosaki, A.; Hayashida, K.; Kawazu, C.; Murata, M.; Nishiyori, H.; Fukuda, S.; Kawai, J.; Daub, C. O.; Hume, D. A.; Suzuki, H.; Orlando, V.; Carninci, P.; Hayashizaki, Y.; Mattick, J. S.

Erratum: Tiny RNAs associated with transcription start sites in animals (Nature Genetics (2009) 41 (572-578)). (Journal Article)

In: Nature Genetics, vol. 41, no. 7, pp. 859, 2009, ISSN: 10614036.

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Taft, R. J.; Glazov, E. A.; Cloonan, N.; Simons, C.; Stephen, S.; Faulkner, G. J.; Lassmann, T.; Forrest, A. R. R.; Grimmond, S. M.; Schroder, K.; Irvine, K.; Arakawa, T.; Nakamura, M.; Kubosaki, A.; Hayashida, K.; Kawazu, C.; Murata, M.; Nishiyori, H.; Fukuda, S.; Kawai, J.; Daub, C. O.; Hume, D. A.; Suzuki, H.; Orlando, V.; Carninci, P.; Hayashizaki, Y.; Mattick, J. S.

Tiny RNAs associated with transcription start sites in animals (Journal Article)

In: Nature Genetics, vol. 41, no. 5, pp. 572–578, 2009, ISSN: 10614036.

(Abstract | Links | BibTeX | Altmetric)

2008

Maeda, N.; Nishiyori, H.; Nakamura, M.; Kawazu, C.; Murata, M.; Sano, H.; Hayashida, K.; Fukuda, S.; Tagami, M.; Hasegawa, A.; Murakami, K.; Schroder, K.; Irvine, K.; Hume, D. A.; Hayashizaki, Y.; Carninci, P.; Suzuki, H.

Development of a DNA barcode tagging method for monitoring dynamic changes in gene expression by using an ultra high-throughput sequencer (Journal Article)

In: BioTechniques, vol. 45, no. 1, pp. 95–97, 2008, ISSN: 07366205.

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2007

Schroder, K.; Spille, M.; Pilz, A.; Lattin, J.; Bode, K. A.; Irvine, K. M.; Burrows, A. D.; Ravasi, T.; Weighardt, H.; Stacey, K. J.; Decker, T.; Hume, D. A.; Dalpke, A. H.; Sweet, M. J.

Differential effects of CpG DNA on IFN-β induction and STAT1 activation in murine macrophages versus dendritic cells: Alternatively activated STAT1 negatively regulates TLR signaling in macrophages (Journal Article)

In: Journal of Immunology, vol. 179, no. 6, pp. 3495–3503, 2007, ISSN: 00221767, (Publisher: American Association of Immunologists).

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Schroder, K.; Lichtinger, M.; Irvine, K. M.; Brion, K.; Trieu, A.; Ross, I. L.; Ravasi, T.; Stacey, K. J.; Rehli, M.; Hume, D. A.; Sweet, M. J.

PU.1 and ICSBP control constitutive and IFN-γ-regulated Tlr9 gene expression in mouse macrophages (Journal Article)

In: Journal of Leukocyte Biology, vol. 81, no. 6, pp. 1577–1590, 2007, ISSN: 07415400.

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Ripoll, V. M.; Irvine, K. M.; Ravasi, T.; Sweet, M. J.; Hume, D. A.

Gpnmb is induced in macrophages by IFN-γ and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses (Journal Article)

In: Journal of Immunology, vol. 178, no. 10, pp. 6559–6566, 2007, ISSN: 00221767, (Publisher: American Association of Immunologists).

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2006

Irvine, K. M.; Burns, C. J.; Wilks, A. F.; Su, S.; Hume, D. A.; Sweet, M. J.

A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations (Journal Article)

In: FASEB Journal, vol. 20, no. 11, pp. E1315–E1326, 2006, ISSN: 08926638.

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2004

Irvine, K.; Stirling, R.; Hume, D.; Kennedy, D.

Rasputin, more promiscuous than ever: A review of G3BP (Journal Article)

In: International Journal of Developmental Biology, vol. 48, no. 10, pp. 1065–1077, 2004, ISSN: 02146282.

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