David Hume

Google Scholar Profile

University of Queensland Research Profile

ORCID 0000-0002-2615-1478

Biography

Professor David Hume FMedSci FRSE graduated with First Class Honours and a PhD in biochemistry from the Australian National University.  He did his postdoctoral research in the Sir William Dunn School of Pathology in Oxford with Siamon Gordon, where he established his career focus on the biology of macrophages.  This research was recognised with the Bonazinga Award for Excellence from the Society for Leukocyte Biology in 2011.  He was subsequently a Research Fellow at the John Curtin School of Medical Research in Canberra and MD Anderson Cancer Center in Houston before joining  the nascent Centre for Molecular Biology and Biotechnology at the University of Queensland in 1988.  This Centre grew over the next 20 years to become the Institute for Molecular Bioscience (IMB).  At the IMB he was Director of the ARC Centre for Functional and Applied Genomics and Deputy Director of the CRC for Chronic Inflammatory Diseases.  He has published extensively on transcription regulation and transcriptomics and from 2000 to 2015 he was a senior member of the FANTOM Consortium, led by RIKEN in Japan.  In 2006, he was appointed Director of The Roslin Institute at the University of Edinburgh and expanded his interests in both macrophage biology and transcriptomics to multiple species other than humans and experimental animals.  He returned to Australia in 2018 and is currently a Professorial Fellow at Mater Research Institute-University of Queensland where he shares a research group with Dr Kate Irvine.  He currently holds an NHMRC-funded Investigator Grant and grant funding from the Australian Research Council.  His major focus is on the regulation and function of the macrophage colony-stimulating factor receptor (CSF1R) and potential utility of the major ligand (CSF1) in tissue repair and regenerative medicine.

Current and recent research funding

2018-2020         Osteal macrophages as therapeutic targets for fracture repair.  A.Pettit, DA Hume, M Wullschleger, L Raggatt, J. Prins.  NHMRC $638,000

2019-2021         CSF1R and the control of microglial function.  DA Hume, KM Summers NHMRC $467,127

2019-2021         CSF1 therapy for chronic liver disease.  KM Irvine, DA Hume, J. Fawcett, A.Clouston NHMRC $497,127

2021-2023         Macrophage control of mammalian growth and development  Australian Research Council Discovery Grant.  DA Hume, KM Irvine, C. Pridans $564,600

2022-2026         Macrophage Biology in Health and Disease.  NHMRC Leadership L3 Investigator Grant. $3,474,000



Publications:

497 entries « 1 of 10 »

2022

Bradford, Barry M; McGuire, Lynne I; Hume, David A; Pridans, Clare; Mabbott, Neil A

Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain (Journal Article)

In: Glia, 2022, ISSN: 1098-1136.

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Shabestari, Sepideh Kiani; Morabito, Samuel; Danhash, Emma Pascal; McQuade, Amanda; Sanchez, Jessica Ramirez; Miyoshi, Emily; Chadarevian, Jean Paul; Claes, Christel; Coburn, Morgan Alexandra; Hasselmann, Jonathan; Hidalgo, Jorge; Tran, Kayla Nhi; Martini, Alessandra C; Rothermich, Winston Chang; Pascual, Jesse; Head, Elizabeth; Hume, David A; Pridans, Clare; Davtyan, Hayk; Swarup, Vivek; Blurton-Jones, Mathew

Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice (Journal Article)

In: Cell Rep, vol. 39, no. 11, pp. 110961, 2022, ISSN: 2211-1247.

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Stables, Jennifer; Green, Emma K; Sehgal, Anuj; Patkar, Omkar L; Keshvari, Sahar; Taylor, Isis; Ashcroft, Maisie E; Grabert, Kathleen; Wollscheid-Lengeling, Evi; Szymkowiak, Stefan; McColl, Barry W; Adamson, Antony; Humphreys, Neil E; Mueller, Werner; Starobova, Hana; Vetter, Irina; Shabestari, Sepideh Kiani; Blurton-Jones, Matthew M; Summers, Kim M; Irvine, Katharine M; Pridans, Clare; Hume, David A

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling (Journal Article)

In: Development, vol. 149, no. 8, 2022, ISSN: 1477-9129.

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Summers, Kim M; Bush, Stephen J; Wu, Chunlei; Hume, David A

Generation and network analysis of an RNA-seq transcriptional atlas for the rat (Journal Article)

In: NAR Genom Bioinform, vol. 4, no. 1, pp. lqac017, 2022, ISSN: 2631-9268.

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Keshvari, Sahar; Genz, Berit; Teakle, Ngari; Caruso, Melanie; Cestari, Michelle F; Patkar, Omkar L; Tse, Brian W C; Sokolowski, Kamil A; Ebersbach, Hilmar; Jascur, Julia; MacDonald, Kelli P A; Miller, Gregory; Ramm, Grant A; Pettit, Allison R; Clouston, Andrew D; Powell, Elizabeth E; Hume, David A; Irvine, Katharine M

Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease (Journal Article)

In: Dis Model Mech, 2022, ISSN: 1754-8411.

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Wu, Zhiguang; Hu, Tuanjun; Chintoan-Uta, Cosmin; Macdonald, Joni; Stevens, Mark P; Sang, Helen; Hume, David A; Kaiser, Pete; Balic, Adam

Development of novel reagents to chicken FLT3, XCR1 and CSF2R for the identification and characterization of avian conventional dendritic cells (Journal Article)

In: Immunology, vol. 165, no. 2, pp. 171–194, 2022, ISSN: 1365-2567.

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Freeman, Tom C; Horsewell, Sebastian; Patir, Anirudh; Harling-Lee, Josh; Regan, Tim; Shih, Barbara B; Prendergast, James; Hume, David A; Angus, Tim

Graphia: A platform for the graph-based visualisation and analysis of high dimensional data (Journal Article)

In: PLoS Comput Biol, vol. 18, no. 7, pp. e1010310, 2022, ISSN: 1553-7358.

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Hume, David A; Offermanns, Stefan; Bonnavion, Remy

Contamination of isolated mouse Kupffer cells with liver sinusoidal endothelial cells ()

2022.

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Laviron, Marie; Petit, Maxime; Weber-Delacroix, Eléonore; Combes, Alexis J; Arkal, Arjun Rao; Barthélémy, Sandrine; Courau, Tristan; Hume, David A; Combadière, Christophe; Krummel, Matthew F; Boissonnas, Alexandre

Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer (Journal Article)

In: Cell Rep, vol. 39, no. 8, pp. 110865, 2022, ISSN: 2211-1247.

(Abstract | Links | BibTeX | Altmetric)

2021

Kaur, Simranpreet; Sehgal, Anuj; Wu, Andy C.; Millard, Susan M.; Batoon, Lena; Sandrock, Cheyenne J.; Ferrari-Cestari, Michelle; Levesque, Jean-Pierre; Hume, David A.; Raggatt, Liza J.; Pettit, Allison R.

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice (Journal Article)

In: Journal of Hematology & Oncology, vol. 14, no. 1, pp. 3, 2021, ISSN: 1756-8722.

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Batoon, Lena; Millard, Susan M.; Raggatt, Liza J.; Sandrock, Cheyenne; Pickering, Edmund; Williams, Kyle; Sun, Lucas W. H.; Wu, Andy C.; Irvine, Katharine M.; Pivonka, Peter; Glatt, Vaida; Wullschleger, Martin E.; Hume, David A.; Pettit, Allison R.

Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones (Journal Article)

In: Biomaterials, vol. 275, pp. 120936, 2021, ISSN: 0142-9612.

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Keshvari, Sahar; Caruso, Melanie; Teakle, Ngari; Batoon, Lena; Sehgal, Anuj; Patkar, Omkar L.; Ferrari-Cestari, Michelle; Snell, Cameron E.; Chen, Chen; Stevenson, Alex; Davis, Felicity M.; Bush, Stephen J.; Pridans, Clare; Summers, Kim M.; Pettit, Allison R.; Irvine, Katharine M.; Hume, David A.

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation (Journal Article)

In: PLOS Genetics, vol. 17, no. 6, pp. e1009605, 2021, ISSN: 1553-7404.

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Hume, David A.; Caruso, Melanie; Keshvari, Sahar; Patkar, Omkar L.; Sehgal, Anuj; Bush, Stephen J.; Summers, Kim M.; Pridans, Clare; Irvine, Katharine M.

The Mononuclear Phagocyte System of the Rat (Journal Article)

In: The Journal of Immunology, vol. 206, no. 10, pp. 2251–2263, 2021, ISSN: 0022-1767, 1550-6606.

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Sehgal, Anuj; Irvine, Katharine M; Hume, David A

Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair (Journal Article)

In: Semin Immunol, vol. 54, pp. 101509, 2021, ISSN: 1096-3618.

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Kaur, Simranpreet; Sehgal, Anuj; Wu, Andy C; Millard, Susan M; Batoon, Lena; Sandrock, Cheyenne J; Ferrari-Cestari, Michelle; Levesque, Jean-Pierre; Hume, David A; Raggatt, Liza J; Pettit, Allison R

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice (Journal Article)

In: Journal of Hematology & Oncology, vol. 14, no. 1, pp. 3, 2021, ISSN: 1756-8722.

(Abstract | Links | BibTeX | Altmetric)

Keshvari, Sahar; Caruso, Melanie; Teakle, Ngari; Batoon, Lena; Sehgal, Anuj; Patkar, Omkar L; Ferrari-Cestari, Michelle; Snell, Cameron E; Chen, Chen; Stevenson, Alex; Davis, Felicity M; Bush, Stephen J; Pridans, Clare; Summers, Kim M; Pettit, Allison R; Irvine, Katharine M; Hume, David A

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation (Journal Article)

In: PLOS Genetics, vol. 17, no. 6, pp. e1009605, 2021, ISSN: 1553-7404, (Publisher: Public Library of Science).

(Abstract | Links | BibTeX | Altmetric)

Batoon, Lena; Millard, Susan M; Raggatt, Liza J; Sandrock, Cheyenne; Pickering, Edmund; Williams, Kyle; Sun, Lucas W H; Wu, Andy C; Irvine, Katharine M; Pivonka, Peter; Glatt, Vaida; Wullschleger, Martin E; Hume, David A; Pettit, Allison R

Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones (Journal Article)

In: Biomaterials, vol. 275, pp. 120936, 2021, ISSN: 0142-9612.

(Abstract | Links | BibTeX | Altmetric)

Millard, Susan M; Heng, Ostyn; Opperman, Khatora S; Sehgal, Anuj; Irvine, Katharine M; Kaur, Simranpreet; Sandrock, Cheyenne J; Wu, Andy C; Magor, Graham W; Batoon, Lena; Perkins, Andrew C; Noll, Jacqueline E; Zannettino, Andrew C W; Sester, David P; Levesque, Jean-Pierre; Hume, David A; Raggatt, Liza J; Summers, Kim M; Pettit, Allison R

Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues (Journal Article)

In: Cell Rep, vol. 37, no. 8, pp. 110058, 2021, ISSN: 2211-1247.

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Psifidi, A.; Kranis, A.; Rothwell, L. M.; Bremner, A.; Russell, K.; Robledo, D.; Bush, S. J.; Fife, M.; Hocking, P. M.; Banos, G.; Hume, D. A.; Kaufman, J.; Bailey, R. A.; Avendano, S.; Watson, K. A.; Kaiser, P.; Stevens, M. P.

Quantitative trait loci and transcriptome signatures associated with avian heritable resistance to Campylobacter (Journal Article)

In: Scientific Reports, vol. 11, no. 1, 2021, ISSN: 20452322, (Publisher: Nature Research).

(Abstract | Links | BibTeX | Altmetric)

Gažová, I.; Lefevre, L.; Bush, S. J.; Rojo, R.; Hume, D. A.; Lengeling, A.; Summers, K. M.

CRISPR-Cas9 Editing of Human Histone Deubiquitinase Gene USP16 in Human Monocytic Leukemia Cell Line THP-1 (Journal Article)

In: Frontiers in Cell and Developmental Biology, vol. 9, 2021, ISSN: 2296634X, (Publisher: Frontiers Media S.A.).

(Abstract | Links | BibTeX | Altmetric)

Patkar, O. L.; Caruso, M.; Teakle, N.; Keshvari, S.; Bush, S. J.; Pridans, C.; Belmer, A.; Summers, K. M.; Irvine, K. M.; Hume, D. A.

Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations (Journal Article)

In: Neurobiology of Disease, vol. 151, 2021, ISSN: 09699961, (Publisher: Academic Press Inc.).

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Wiener, P.; Robert, C.; Ahbara, A.; Salavati, M.; Abebe, A.; Kebede, A.; Wragg, D.; Friedrich, J.; Vasoya, D.; Hume, D. A.; Djikeng, A.; Watson, M.; Prendergast, J. G. D.; Hanotte, O.; Mwacharo, J. M.; Clark, E. L.

Whole-Genome Sequence Data Suggest Environmental Adaptation of Ethiopian Sheep Populations (Journal Article)

In: Genome biology and evolution, vol. 13, no. 3, 2021, ISSN: 17596653, (Publisher: NLM (Medline)).

(Abstract | Links | BibTeX | Altmetric)

Karagianni, A. E.; Lisowski, Z. M.; Hume, D. A.; Pirie, R. Scott

The equine mononuclear phagocyte system: The relevance of the horse as a model for understanding human innate immunity (Journal Article)

In: Equine Veterinary Journal, vol. 53, no. 2, pp. 231–249, 2021, ISSN: 04251644, (Publisher: Equine Veterinary Journal Ltd).

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Pridans, C.; Irvine, K. M.; Davis, G. M.; Lefevre, L.; Bush, S. J.; Hume, D. A.

Transcriptomic Analysis of Rat Macrophages (Journal Article)

In: Frontiers in Immunology, vol. 11, 2021, ISSN: 16643224, (Publisher: Frontiers Media S.A.).

(Abstract | Links | BibTeX | Altmetric)

Green, K. N.; Hume, D. A.

On the utility of CSF1R inhibitors (Journal Article)

In: Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 4, 2021, ISSN: 00278424, (Publisher: National Academy of Sciences).

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Lisowski, Z. M.; Lefevre, L.; Mair, T. S.; Clark, E. L.; Hudson, N. P. H.; Hume, D. A.; Pirie, R. S.

Use of quantitative real-time PCR to determine the local inflammatory response in the intestinal mucosa and muscularis of horses undergoing small intestinal resection (Journal Article)

In: Equine Veterinary Journal, 2021, ISSN: 04251644, (Publisher: Equine Veterinary Journal Ltd).

(Abstract | Links | BibTeX | Altmetric)

2020

Grabert, Kathleen; Sehgal, Anuj; Irvine, Katharine M.; Wollscheid-Lengeling, Evi; Ozdemir, Derya D.; Stables, Jennifer; Luke, Garry A.; Ryan, Martin D.; Adamson, Antony; Humphreys, Neil E.; Sandrock, Cheyenne J.; Rojo, Rocio; Verkasalo, Veera A.; Mueller, Werner; Hohenstein, Peter; Pettit, Allison R.; Pridans, Clare; Hume, David A.

A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System (Journal Article)

In: The Journal of Immunology, vol. 205, no. 11, pp. 3154–3166, 2020, ISSN: 0022-1767, 1550-6606.

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Irvine, Katharine M.; Caruso, Melanie; Cestari, Michelle Ferrari; Davis, Gemma M.; Keshvari, Sahar; Sehgal, Anuj; Pridans, Clare; Hume, David A.

Analysis of the impact of CSF‐1 administration in adult rats using a novel textitCsf1r ‐mApple reporter gene (Journal Article)

In: Journal of Leukocyte Biology, vol. 107, no. 2, pp. 221–235, 2020, ISSN: 0741-5400, 1938-3673.

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Munro, D. A. D.; Bradford, B. M.; Mariani, S. A.; Hampton, D. W.; Vink, C. S.; Chandran, S.; Hume, D. A.; Pridans, C.; Priller, J.

CNS macrophages differentially rely on an intronic Csf1r enhancer for their development (Journal Article)

In: Development (Cambridge), vol. 147, no. 23, 2020, ISSN: 09501991, (Publisher: Company of Biologists Ltd).

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Dutta, P.; Talenti, A.; Young, R.; Jayaraman, S.; Callaby, R.; Jadhav, S. K.; Dhanikachalam, V.; Manikandan, M.; Biswa, B. B.; Low, W. Y.; Williams, J. L.; Cook, E.; Toye, P.; Wall, E.; Djikeng, A.; Marshall, K.; Archibald, A. L.; Gokhale, S.; Kumar, S.; Hume, D. A.; Prendergast, J. G. D.

Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication (Journal Article)

In: Nature Communications, vol. 11, no. 1, 2020, ISSN: 20411723, (Publisher: Nature Research).

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Wragg, D.; Liu, Q.; Lin, Z.; Riggio, V.; Pugh, C. A.; Beveridge, A. J.; Brown, H.; Hume, D. A.; Harris, S. E.; Deary, I. J.; Tenesa, A.; Prendergast, J. G. D.

Using regulatory variants to detect gene–gene interactions identifies networks of genes linked to cell immortalisation (Journal Article)

In: Nature Communications, vol. 11, no. 1, 2020, ISSN: 20411723, (Publisher: Nature Research).

(Abstract | Links | BibTeX | Altmetric)

Summers, K. M.; Bush, S. J.; Hume, D. A.

Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system (Journal Article)

In: PLoS Biology, vol. 18, no. 10, 2020, ISSN: 15449173, (Publisher: Public Library of Science).

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Gow, D. J.; Jackson, H.; Forsythe, P.; Nuttall, T.; Gow, A. G.; Mellanby, R. J.; Hume, D. A.

Measurement of serum Interleukin 34 (IL-34) and correlation with severity and pruritus scores in client-owned dogs with atopic dermatitis (Journal Article)

In: Veterinary Dermatology, vol. 31, no. 5, pp. 359–e94, 2020, ISSN: 09594493, (Publisher: Blackwell Publishing Ltd).

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Tsang, H. -G.; Clark, E. L.; Markby, G. R.; Bush, S. J.; Hume, D. A.; Corcoran, B. M.; MacRae, V. E.; Summers, K. M.

Expression of Calcification and Extracellular Matrix Genes in the Cardiovascular System of the Healthy Domestic Sheep (Ovis aries) (Journal Article)

In: Frontiers in Genetics, vol. 11, 2020, ISSN: 16648021, (Publisher: Frontiers Media S.A.).

(Abstract | Links | BibTeX | Altmetric)

Lisowski, Z. M.; Sauter, K. A.; Waddell, L. A.; Hume, D. A.; Pirie, R. S.; Hudson, N. P. H.

Immunohistochemical study of morphology and distribution of CD163+ve macrophages in the normal adult equine gastrointestinal tract (Journal Article)

In: Veterinary Immunology and Immunopathology, vol. 226, 2020, ISSN: 01652427, (Publisher: Elsevier B.V.).

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Bush, S. J.; McCulloch, M. E. B.; Lisowski, Z. M.; Muriuki, C.; Clark, E. L.; Young, R.; Pridans, C.; Prendergast, J. G. D.; Summers, K. M.; Hume, D. A.

Species-Specificity of Transcriptional Regulation and the Response to Lipopolysaccharide in Mammalian Macrophages (Journal Article)

In: Frontiers in Cell and Developmental Biology, vol. 8, 2020, ISSN: 2296634X, (Publisher: Frontiers Media S.A.).

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Gažová, I.; Lefevre, L.; Bush, S. J.; Clohisey, S.; Arner, E.; Hoon, M.; Severin, J.; Duin, L.; Andersson, R.; Lengeling, A.; Hume, D. A.; Summers, K. M.

The Transcriptional Network That Controls Growth Arrest and Macrophage Differentiation in the Human Myeloid Leukemia Cell Line THP-1 (Journal Article)

In: Frontiers in Cell and Developmental Biology, vol. 8, 2020, ISSN: 2296634X, (Publisher: Frontiers Media S.A.).

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Clohisey, S.; Parkinson, N.; Wang, B.; Bertin, N.; Wise, H.; Tomoiu, A.; Summers, K. M.; Hendry, R. W.; Carninci, P.; Forrest, A. P. R.; Hayashizaki, Y.; Digard, P.; Hume, D. A.; Baillie, J. K.

Comprehensive characterization of transcriptional activity during influenza a virus infection reveals biases in cap-snatching of host rna sequences (Journal Article)

In: Journal of Virology, vol. 94, no. 10, 2020, ISSN: 0022538X, (Publisher: American Society for Microbiology).

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Wu, Z.; Harne, R.; Chintoan-Uta, C.; Hu, T. -J.; Wallace, R.; MacCallum, A.; Stevens, M. P.; Kaiser, P.; Balic, A.; Hume, D. A.

Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune system (Journal Article)

In: Developmental and Comparative Immunology, vol. 105, 2020, ISSN: 0145305X, (Publisher: Elsevier Ltd).

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Summers, K. M.; Bush, S. J.; Wu, C.; Su, A. I.; Muriuki, C.; Clark, E. L.; Finlayson, H. A.; Eory, L.; Waddell, L. A.; Talbot, R.; Archibald, A. L.; Hume, D. A.

Functional Annotation of the Transcriptome of the Pig, Sus scrofa, Based Upon Network Analysis of an RNAseq Transcriptional Atlas (Journal Article)

In: Frontiers in Genetics, vol. 10, 2020, ISSN: 16648021, (Publisher: Frontiers Media S.A.).

(Abstract | Links | BibTeX | Altmetric)

Hume, D. A.; Caruso, M.; Ferrari-Cestari, M.; Summers, K. M.; Pridans, C.; Irvine, K. M.

Phenotypic impacts of CSF1R deficiencies in humans and model organisms (Journal Article)

In: Journal of Leukocyte Biology, vol. 107, no. 2, pp. 205–219, 2020, ISSN: 07415400, (Publisher: John Wiley and Sons Inc.).

(Abstract | Links | BibTeX | Altmetric)

Hume, D. A.; Gutowska-Ding, M. W.; Garcia-Morales, C.; Kebede, A.; Bamidele, O.; Trujillo, A. V.; Gheyas, A. A.; Smith, J.

Functional evolution of the colony-stimulating factor 1 receptor (CSF1R) and its ligands in birds (Journal Article)

In: Journal of Leukocyte Biology, vol. 107, no. 2, pp. 237–250, 2020, ISSN: 07415400, (Publisher: John Wiley and Sons Inc.).

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Warr, A.; Affara, N.; Aken, B.; Beiki, H.; Bickhart, D. M.; Billis, K.; Chow, W.; Eory, L.; Finlayson, H. A.; Flicek, P.; Girón, C. G.; Griffin, D. K.; Hall, R.; Hannum, G.; Hourlier, T.; Howe, K.; Hume, D. A.; Izuogu, O.; Kim, K.; Koren, S.; Liu, H.; Manchanda, N.; Martin, F. J.; Nonneman, D. J.; O’Connor, R. E.; Phillippy, A. M.; Rohrer, G. A.; Rosen, B. D.; Rund, L. A.; Sargent, C. A.; Schook, L. B.; Schroeder, S. G.; Schwartz, A. S.; Skinner, B. M.; Talbot, R.; Tseng, E.; Tuggle, C. K.; Watson, M.; Smith, T. P. L.; Archibald, A. L.

An improved pig reference genome sequence to enable pig genetics and genomics research (Journal Article)

In: GigaScience, vol. 9, no. 6, 2020, ISSN: 2047217X, (Publisher: Oxford University Press).

(Abstract | Links | BibTeX | Altmetric)

Hume, D.; Mackay, J. M.

Poorly connected groups (Journal Article)

In: Proceedings of the American Mathematical Society, vol. 148, no. 11, pp. 4653–4664, 2020, ISSN: 00029939, (Publisher: American Mathematical Society).

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Wittenberg, G. M.; Stylianou, A.; Zhang, Y.; Sun, Y.; Gupta, A.; Jagannatha, P. S.; Wang, D.; Hsu, B.; Curran, M. E.; Khan, S.; Vértes, P. E.; Cardinal, R.; Richardson, S.; Leday, G.; Freeman, T.; Hume, D.; Regan, T.; Wu, Z.; Pariante, C.; Cattaneo, A.; Zunszain, P.; Borsini, A.; Stewart, R.; Chandran, D.; Carvalho, L.; Bell, J.; Souza-Teodoro, L. H.; Perry, H.; Harrison, N.; Jones, D.; Henderson, R. B.; Chen, G.; Bullmore, E. T.; Drevets, W. C.; Consortium, MRC ImmunoPsychiatry

Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders (Journal Article)

In: Molecular Psychiatry, vol. 25, no. 6, pp. 1275–1285, 2020, ISSN: 13594184, (Publisher: Springer Nature).

(Abstract | Links | BibTeX | Altmetric)

Abbott, C. R.; Hume, D.

The geometry of generalized loxodromic elements (Journal Article)

In: Annales de l’Institut Fourier, vol. 70, no. 4, pp. 1689–1713, 2020, ISSN: 03730956, (Publisher: Association des Annales de l’Institut Fourier).

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2019

Rojo, R.; Raper, A.; Ozdemir, D. D.; Lefevre, L.; Grabert, K.; Wollscheid-Lengeling, E.; Bradford, B.; Caruso, M.; Gazova, I.; Sánchez, A.; Lisowski, Z. M.; Alves, J.; Molina-Gonzalez, I.; Davtyan, H.; Lodge, R. J.; Glover, J. D.; Wallace, R.; Munro, D. A. D.; David, E.; Amit, I.; Miron, V. E.; Priller, J.; Jenkins, S. J.; Hardingham, G. E.; Blurton-Jones, M.; Mabbott, N. A.; Summers, K. M.; Hohenstein, P.; Hume, D. A.; Pridans, C.

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations (Journal Article)

In: Nature Communications, vol. 10, no. 1, 2019, ISSN: 20411723, (Publisher: Nature Publishing Group).

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Low, W. Y.; Tearle, R.; Bickhart, D. M.; Rosen, B. D.; Kingan, S. B.; Swale, T.; Thibaud-Nissen, F.; Murphy, T. D.; Young, R.; Lefevre, L.; Hume, D. A.; Collins, A.; Ajmone-Marsan, P.; Smith, T. P. L.; Williams, J. L.

Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity (Journal Article)

In: Nature Communications, vol. 10, no. 1, 2019, ISSN: 20411723, (Publisher: Nature Publishing Group).

(Abstract | Links | BibTeX | Altmetric)

Freem, L.; Summers, K. M.; Gheyas, A. A.; Psifidi, A.; Boulton, K.; MacCallum, A.; Harne, R.; O’Dell, J.; Bush, S. J.; Hume, D. A.

Analysis of the Progeny of Sibling Matings Reveals Regulatory Variation Impacting the Transcriptome of Immune Cells in Commercial Chickens (Journal Article)

In: Frontiers in Genetics, vol. 10, 2019, ISSN: 16648021, (Publisher: Frontiers Media S.A.).

(Abstract | Links | BibTeX | Altmetric)

Muriuki, C.; Bush, S. J.; Salavati, M.; McCulloch, M. E. B.; Lisowski, Z. M.; Agaba, M.; Djikeng, A.; Hume, D. A.; Clark, E. L.

A Mini-Atlas of Gene Expression for the Domestic Goat (Capra hircus) (Journal Article)

In: Frontiers in Genetics, vol. 10, 2019, ISSN: 16648021, (Publisher: Frontiers Media S.A.).

(Abstract | Links | BibTeX | Altmetric)

497 entries « 1 of 10 »