Stephen Huang

Stephen Huang received his PhD in 2019 from the University of Queensland studying transcription factors critical for red blood cell development and how mutations in these can cause disease. During his training he studied the functions of KLF1, a transcription factor critical for red blood cell development. Mutations identified in KLF1 can cause red cell disease. He established a mouse model of non-spherocytic haemolytic anaemia (NSHA), which phenocopies the human disease, to understand the contribution and function of mutations in KLF1. After his PhD he joined the lab of Dr. Lachlan Rash studying the biological effects of peptide inhibitors of acid sensing ion channels. His research during this time was to understand the contributions of acidosis to the tumor micro-environment and how acidosis can elicit changes to encourage epithelial to mesenchymal transition.

In 2022 he joined the macrophage biology lab led by David Hume and Kate Irvine. His research interests are in understanding the contributions of CSF1R in developmental haematopoiesis, embryonic development, implantation, and changes to macrophages under pathophysiological conditioning.