Jennifer Stables

Biography

Jen joined the Macrophage Biology group to undertake her PhD in July 2019. She is studying a novel model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP). Patients with this form of early-onset dementia have amino acid substitutions in the tyrosine kinase domain of CSF1R. She hopes to unravel the molecular mechanisms that lead to the pathogenesis of ALSP. Prior to joining the lab, Jen was awarded a BSc with First Class Honours (Neuroscience) and University Medal from The University of Queensland. After completing her honours, Jen worked as a Forensic Histologist and then as a Research Assistant at Mater Research. During her candidature she has received numerous awards, most recently, Student Researcher of the Year for the PAH Health Symposium’s Laboratory/Basic Science Category. In addition to her research, Jen is a passionate educator and is an Associate Fellow of the Higher Education Academy.


Research Links:


Publications

2022

Stables, Jennifer; Green, Emma K; Sehgal, Anuj; Patkar, Omkar L; Keshvari, Sahar; Taylor, Isis; Ashcroft, Maisie E; Grabert, Kathleen; Wollscheid-Lengeling, Evi; Szymkowiak, Stefan; McColl, Barry W; Adamson, Antony; Humphreys, Neil E; Mueller, Werner; Starobova, Hana; Vetter, Irina; Shabestari, Sepideh Kiani; Blurton-Jones, Matthew M; Summers, Kim M; Irvine, Katharine M; Pridans, Clare; Hume, David A

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling (Journal Article)

In: Development, vol. 149, no. 8, 2022, ISSN: 1477-9129.

(Abstract | Links | BibTeX | Altmetric)

2020

Grabert, Kathleen; Sehgal, Anuj; Irvine, Katharine M.; Wollscheid-Lengeling, Evi; Ozdemir, Derya D.; Stables, Jennifer; Luke, Garry A.; Ryan, Martin D.; Adamson, Antony; Humphreys, Neil E.; Sandrock, Cheyenne J.; Rojo, Rocio; Verkasalo, Veera A.; Mueller, Werner; Hohenstein, Peter; Pettit, Allison R.; Pridans, Clare; Hume, David A.

A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System (Journal Article)

In: The Journal of Immunology, vol. 205, no. 11, pp. 3154–3166, 2020, ISSN: 0022-1767, 1550-6606.

(Links | BibTeX | Altmetric)